Buffalo Bills at Indianapolis Colts: Predictions, Tips, Odds

by Junna Base November 10, 2024

The Buffalo Bills (7-2) are on the rise and can get closer to a division title when they play the Indianapolis Colts (4-5) on Sunday.

Tyler Bass’ leg kept Buffalo’s winning streak alive as the team has completely separated itself from the rest of the AFC East. The Bills lead the division by more than three games and could theoretically win the title before the end of the month. This goal can become possible with another victory.

Joe Flacco couldn’t make magic when he stepped in as the starting quarterback for Indianapolis as the offense failed to reach the end zone in Sunday night’s loss to Minnesota. The Colts will expect him to be able to turn the tide as they face one of the league’s top-scoring defenses.

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Colts vs. Bills Odds, Moneyline, Over/Under

According to BetMGM NFL odds, the Bills are the favorites to win over the Colts. Would you like to bet? Check out the best mobile sports betting apps offering NFL betting promotions in 2024, including the ESPN BET app and Fanatics Sportsbook promo code.

Spread: Bills (-4)
Moneyline: Bills (-210); Colt (+170)
Over/under: 46.5

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NFL Week 10 odds, predictions and picks

Lorenzo Reyes: Bills 28, Colts 17

The Colts have mismanaged their quarterback situation and Indianapolis has become one-dimensional without the pressing threat that Anthony Richardson brings. The Bills’ defense has its weaknesses, but Buffalo should be able to outscore the Colts with relative ease.

Tyler Dragon: Bills 28, Colts 18

I disagree with the demotion of Anthony Richardson. The Colts made a hasty decision on Richardson, who is a talented quarterback but needs time to develop. The Bills are trying to win the AFC East. They currently have a four-game lead.

Richard Morin: Bills 33, Colts 10

The Colts are quickly losing ground and have made a mess of the quarterback situation. The Bills, meanwhile, are on their way to a high playoff spot

Jordan Mendoza: Bills 31, Colts 23

The Bills were among the league’s most accurate offenses, while Indianapolis struggled to stop teams from moving the ball. As long as Buffalo plays a clean game, the fifth win in a row should be easy.

(This story has been updated to change a video.)

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