Can a diabetes drug and immunotherapy help treat brain cancer?

A new strategy for treating glioblastoma is to boost the tumor-killing abilities of immune cells. Although tumor-fighting CD8+ T cells are capable of eliminating tumors, cancer would reduce their effectiveness, she explained. Efforts to counteract this dysfunction have not yet proven successful. However, Dr. Bayik and her team recently found that DPP-4 is present in large quantities on dysfunctional T cells, giving her hope.